Metabolic and Nutrition Phenotyping Core Facility:Body Composition, Bone Mineral Density, and Trace Element Analysis

The Department of Nutritional Sciences Core Facility houses equipment available for use (with user fees) to researchers across OSU campuses. Hologic Discovery QDR Series Dual-Energy X-ray Absorptiometer (DEXA): DEXA is the industry standard for measuring both human and animal bone density, but is also a valuable tool for assessing body composition (lean body mass and adipose). Currently, this equipment is utilized by researchers in the Department of Nutritional Sciences, in addition to other departments on campus, to determine the effects of dietary and environmental factors on bone mineral density; however, it is also useful for analyzing other hard tissue parameters. Through a collaborative effort, the Department of Nutritional Sciences and the Oklahoma State University Athletic Department has initiated a series of studies examining the bone mineral density and body composition of collegiate athletes. Faculty Contacts: Drs.
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Scanco Medical mCT 40: This mCT unit is designed to scan small bone specimens (i.e., rodent or larger animal biopsies) to create a three-dimensional model without damaging the original biological specimen. The mCT is used in the Department to examine the effects of various physiological conditions (i.e., hormone or nutrient deficiencies) on bone microarchitecture. Specimens can be scanned both in the absence of presence of solution (i.e., formalin fixative). Departmental faculty members provide analytical services to other investigators across campus to assess the structural and biomechanical properties of bone. Faculty Contacts: Drs.
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Lunar Piximus: This pencil-beam DEXA allows for the determination of bone mineral density and body composition of small animal models (i.e., Mus musculus). Faculty Contacts: Drs.
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Perkin-Elmer Elan 9000 Inductively Coupled Plasma-Mass Spectrometer (ICP-MS): ICP-MS is a highly sensitive method useful for determining the concentration of metals and some non-metals below one part in 1012. ICP-MS can be used for the elemental analysis of both biological (e.g., blood or urine) and environmental (e.g., water) samples. The Department of Nutritional Sciences is currently utilizing ICP-MS analysis to measure trace minerals in blood, serum, and food, but it can also be used for mineral and isotope analyses of environmental samples (e.g., water or soil samples). Faculty Contact: Dr.
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For more general information regarding available equipment and services, please contact:
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, Research Analyst Department of Nutritional Sciences 415 HES (405) 744-3003
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